Study type: Medical/biological study (experimental study)

Structural and Ultrastructural Study of Rat Liver Influenced by Electromagnetic Radiation. med./bio.

Published in: J Toxicol Environ Health A 2015; 78 (6): 353-356

Aim of study (acc. to author)

The effects of exposure of rats to a pulsed 2.45 GHz electromagnetic field on the structure and ultrastructure of the liver should be investigated.

Background/further details

40 rats were divided into 2 groups (n=20 each): 1) control group and 2) exposure to the electromagnetic field. All animals were anesthetized and examined 3 hours after the last exposure session.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: continuous for 3 h/day for 3 weeks

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Exposure duration continuous for 3 h/day for 3 weeks
Exposure setup
Exposure source
  • not specified
Chamber purpose-designed chamber
Parameters
Measurand Value Type Method Mass Remarks
power density 2.8 mW/cm² mean - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Microscopy showed a slightly increased blood flow, dilatation of liver sinusoids and small inflammatory foci in the centers of liver lobules in the exposure group compared to the control group. The morphology of hepatocytes was not altered and all observed changes were classified as moderate.
Electron microscopy of hepatocytes revealed more vesicles, lipid droplets and growth of the smooth endoplasmic reticulum in cells of the exposure group compared to the control group. Occasionally, necrotic cells were found in the exposure group but not in the control group.
The authors conclude that exposure of rats to a pulsed 2.45 GHz electromagnetic field could have adverse effects on the liver.

Study character:

Study funded by

Related articles