研究のタイプ: 医学/生物学の研究 (experimental study)

[携帯電話放射へのばく露による成獣および幼若な雄アルビノラット脳のいくつかの領域でのアミノ酸神経伝達物質の変動] med./bio.

Variations in amino acid neurotransmitters in some brain areas of adult and young male albino rats due to exposure to mobile phone radiation.

掲載誌: Eur Rev Med Pharmacol Sci 2011; 15 (7): 729-742

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研究目的(著者による)

To study the effect of one hour daily exposure to electromagnetic fields with a frequency of 900 MHz on the levels of amino acid neurotransmitters in the midbrain, cerebellum and medulla of adult (four month) and young (one month) male rats.

詳細情報

The determination of amino acid levels was carried out after one hour of exposure and following one, two and four months of exposure as well as one month after termination of exposure of four months. The subgroups of the different removed animal groups comprised 5-8 animals.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
ばく露時間: continuous for 1 h/day for up to 4 months

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 1 h/day for up to 4 months
ばく露装置
ばく露の発生源/構造
  • 詳細不明
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
電力密度 0.02 mW/cm² - - - -
SAR 1.165 W/kg - - - -

Reference articles

  • Khadrawy VA et al. (2009): [成獣および幼若ラットの皮質アミノ酸神経伝達物質のレベルに対する携帯電話からの電磁放射の影響]

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

The data showed a significant increase in both excitatory and inhibitory amino acids in the cerebellum of adult and young rats as well as in the midbrain of adult animals after one hour of electromagnetic field exposure. In the midbrain of adult animals, there were significant increases in the glycine level (after one month) and in the GABA level (after one hour and four months).
Young rats showed significant decreases in the midbrain excitatory amino acids.
In the medulla, the data showed a state of neurochemical inhibition in adult animals after four months, whereas in young animals, the neurochemical inhibitory state was observed after one month of exposure due to significant decreases in glutamate and aspartate levels. This state was converted to an excitation state after 4 months due to the increase in glutamate level.
The authors conclude that the changes in amino acid concentrations may underlie adverse effects of mobile phone use.

研究の種別:

研究助成

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