Study type: Medical/biological study (experimental study)

Short-term effects of extremely low frequency electromagnetic fields exposure on Alzheimer's disease in rats. med./bio.

Published in: Int J Radiat Biol 2015; 91 (1): 28-34

Aim of study (acc. to author)

To examine the influence of exposure to extremely low frequency magnetic fields on memory impairment in rats.

Background/further details

Rats were exposed (n=10) or sham exposed (n=10).
At the end of the exposure period, rats were subjected to the Morris water maze. Afterwards, they were killed to remove the brain and take blood samples.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 12 weeks

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for 12 weeks
Exposure setup
Exposure source
Chamber rats were placed in a special plastic box without metallic parts; animals were able to move freely in the box
Setup coil of Helmholtz with two parallel spires (5.2 m Π5.2 m) was used; distance between two coils was 2 m, and one was buried underground for 0.7 m
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 100 µT - measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • before exposure
  • after exposure

Main outcome of study (acc. to author)

No significant differences were observed in the body weight, histopathological examination of the brain, content of beta-amyloid protein, and the performance in the Morris water maze between exposed and sham exposed rats.
The results indicate that exposure to extremely low frequency magnetic fields has no influence on the memory performance of rats.

Study character:

Study funded by

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