Study type: Medical/biological study (experimental study)

900 MHz pulse-modulated radiofrequency radiation induces oxidative stress on heart, lung, testis and liver tissues. med./bio.

Published in: Gen Physiol Biophys 2011; 30 (1): 84-89

Aim of study (acc. to author)

To study whether 900 MHz pulse modulated radiofrequency electromagnetic fields induce oxidative damage in lung, heart, testes and liver tissues.

Background/further details

30 rats were divided into a control group, a sham exposed group and an exposed group (each group n=10).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 20 min/day for 3 weeks
  • SAR: 1.2 W/kg average over mass (whole body)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continuous for 20 min/day for 3 weeks
Modulation
Modulation type pulsed
Pulse width 0.576 ms
Repetition frequency 217 Hz
Pulse type rectangular
Exposure setup
Exposure source
Setup rectangular horn antenna placed under the 15 cm x 20 cm x 20 cm polymethyl methacrylate cages
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 1.2 W/kg average over mass calculated whole body -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Malondialdehyde and nitric oxide levels were significantly increased in liver, lung, testis and heart tissues of the exposed group compared to sham exposed and control groups. Conversely, glutathione levels were significantly lower in exposed rat tissues in comparison with the sham exposed and control group. No significantly difference was observed between the sham exposed group and control group.
The data showed that pulse modulated radiofrequency exposure caused oxidative injury in liver, lung, testis and heart tissues mediated by lipid peroxidation, increased level of nitric oxide and suppression of antioxidant defense mechanism.

Study character:

Study funded by

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