Study type: Medical/biological study (experimental study)

Radiofrequency electromagnetic field exposure effects on antioxidant enzymes and liver function tests. med./bio.

Published in: International Journal of Life Sciences 2012; 1 (3): 233-239

Aim of study (acc. to author)

To examine the influence of exposure to microwaves (2.45 GHz) or to the radiofrequency field of a mobile phone (900 MHz) on the oxidative status of the liver and further liver values in rats.

Background/further details

In the first experiment, rats were exposed (n=6) or sham exposed (n=6) to microwaves (2.45 GHz). In the second experiment, rats were exposed to the radiofrequency field of a mobile phone (900 MHz) (remark EMF-Portal: in the second experiment, no information was given about number of animals and treatment of control animals).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: continuous for 2 hours/day for 35 days
Exposure 2: 900 MHz
Modulation type: pulsed
Exposure duration: intermittend for 2 hours/day for 35 days
-

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Charakteristic
Exposure duration continuous for 2 hours/day for 35 days
Modulation
Modulation type cf. additional info
Additional info

50 Hz modulation frequency

Exposure setup
Exposure source
Chamber plexiglas cage with ventilation holes of 1 cm diameter
Setup exposure cage with animals was kept in an anechoic chamber; a microwave oven was used as exposure source connected to a 40 db attenuation and a horn antenna; animals were facing the horn antenna; temperature was maintained at 25-27°C
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.15 W/kg - estimated whole body -
power density 0.22 mW/cm² - measured - -
power 1,080 W - - - input power
power 700 W - - - output power

Exposure 2

Main characteristics
Frequency 900 MHz
Type
Exposure duration intermittend for 2 hours/day for 35 days
Modulation
Modulation type pulsed
Exposure setup
Exposure source
Chamber plexiglas cage with ventilation holes of 1 cm diameter in which rats were restricted (mobility 1-2 cm) during exposure
Setup exposure cage with animals was kept in an anechoic chamber; GSM mobile phones were kept on the top of the cage in such a configuration that there was preferential emissions towards the animals in the cage; every cage was attached with a seperate mobile phone; cell phone was in standby; calls lasted 1 min (no information given how many calls in the two hours); cell phones were in silent mode without vibration
Parameters

No parameters are specified for this exposure.

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Rats exposed to microwaves (2.45 GHz) or to the radiofrequency field of a mobile phone (900 MHz) showed significantly decreased enzyme activities of the glutathione peroxidase and the superoxide dismutase when compared to the control, while the enzyme activity of the catalase and the lipid peroxidation were significantly increased.
Additionally, all liver values in the serum of exposed rats (microwave or mobile phone) were significantly increased in comparison to the control group.
The authors conclude that exposure to microwaves (2.45 GHz) or to the radiofrequency field of a mobile phone (900 MHz) could lead to oxidative stress in the liver and to increased liver values in rats.

Study character:

Study funded by

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