Study type: Medical/biological study (experimental study)

Reduced weight in mice offspring after in utero exposure to 2450-MHz (CW) microwaves med./bio.

Published in: Bioelectromagnetics 1982; 3 (2): 285-291

Aim of study (acc. to author)

This in vivo study was conducted to examine the effects of 2.45 GHz microwave irradiation during pregnancy on mice fetuses.

Background/further details

The offspring of irradiated dams were examined either as fetuses after hysterotomy (incision in the uterus) on the 18th day of gestation or as naturally born neonates on the 1st and 7th day of age. A total of 50 sham exposed and 50 microwave exposed mice were investigated.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: 100 min/day from 6th-17th day of gestation

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Exposure duration 100 min/day from 6th-17th day of gestation
Additional info Exposure setup has been described before in Berman et al. 1978 (TER-154).
Modulation
Modulation type CW
Exposure setup
Exposure source
Chamber polycarbonate plastic cage
Parameters
Measurand Value Type Method Mass Remarks
SAR 16.5 mW/g mean cf. remarks cf. remarks +/- 4.5 mW/g
power density 280 W/m² - cf. remarks - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The pregnancy rate and the numbers of live, dead, resorbed, total fetuses, and the survival rates of neonates were not statistical significant different in exposure and sham exposure groups.
The mean weight was significantly lower in live microwave-irradiated fetuses, accompanied by delayed sternal ossification which indicates a growth retardation. In the naturally born offspring of irradiated dams a significantly lower mean weight was observed in 7-day-old mice.

Study character:

Study funded by

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