genotoxicity/mutation: in cell studies: mutation, chromosomal damage, DNA damage
cell function: in cell studies: metabolic activity, aggregation and cell adhesion, intracellular signal transduction, orientation
cancer: in animal studies: genotoxicity and mutagenesis, cancer
effects on the reproductive system: in animal studies: fertility, growth and development
cognitive/behavioral endpoints: in animal studies: behavior (e.g. motor activity, taste aversion); in human studies: cognition
effects on the cardiovascular system: in animal studies: blood flow, cardiac function (ECG), blood pressure; in human studies: cardiac function (ECG), blood flow
effects on the neurological system: in animal studies: electrophysiology of neurons and brain (EEG), neuroendocrine system; in human studies: nerve conduction, brain activity (EEG), brain metabolism
hypersensitivity/subjective complaints: in human studies: primary sensory effects
epidemiology: cancer, reproduction and development, immune system
