研究のタイプ: 医学／生物学の研究 (experimental study)

[ナルコレプシー患者の視覚事象電位に携帯電話は影響する] med./bio.

Electromagnetic field of mobile phones affects visual event related potential in patients with narcolepsy

著者: Jech R, Sonka K, Ruzicka E, Nebuzelsky A, Böhm J, Juklickova M, Nevsimalova S
掲載誌: Bioelectromagnetics 2001; 22 (7): 519-528
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この研究は、携帯電話（MP）電磁界（900 MHz、SAR= 0.06 W/ kg）が、脳電図（EEG）および事象関連電位（ERP）に影響するか否かをボランティア実験で調べた。まず、ナルコレプシー（日中の過度の眠気発作）によるカタプレキシー（脱力発作）の併発患者（n = 22）を対象に、右耳の側に固定したMPからのばく露または擬似ばく露（いずれも45分間）を、二重ブラインド化実験法にて実施した。その結果、MPばく露後に記録されたEEGに変化は見られなかった。次に、上記の患者群から抽出したサブグループ（n = 17）を対象に、MPばく露中におけるオドボール課題を用いた視覚的ERPを記録した。オドボール課題とは、同じ標準刺激が繰り返し呈示される中で，稀に異なった刺激(標的刺激)の呈示に反応してキーを押す課題である。この実験では、標的刺激の呈示視野を3通りに変えた：左半側視野、右半側視野、全視野。その結果、MPばく露時に、右半側視野での標的刺激に応答したERPの内因性成分の陽性が増強した（P < 0.01）；すべての標的刺激への反応時間は20 ms短縮された（P < 0.05）、と報告している。

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研究目的（著者による）

To examine the effects of the mobile phone electromagnetic fields on EEG and event-related potentials. The aim was to study in particular patients with narcolepsy in an effort to explore the interaction between vigilance and the effects of the pulsed mobile phone field. In a double-blind study, these patients had the visual event-related potentials recorded during their 45 min exposure.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for 45 min
  • 電力: 2 W maximum
  • SAR: 0.06 W/kg maximum (10 g)

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 45 min
Modulation
Modulation type pulsed
Pulse width 0.577 ms
Repetition frequency 217 Hz
Additional information

modulation frequency components 2 and 8 Hz
ばく露装置
ばく露の発生源／構造
  • セルラ－電話
  • antenna not extended
チャンバの詳細 The patients were examined in the supine position in a darkened room.
ばく露装置の詳細 The mobile phone was fixed to the right ear using a special holder. The phone was thermally insulated from the head with a textile case and the electrode cap. It was not possible to recognise the state of exposure.
Additional information The patients were examined in a double blind study on two successive days with 50% of them per day being exposed or sham exposed.
パラメータ
測定量 値 種別 Method Mass 備考
電力 2 W maximum - - -
SAR 0.06 W/kg maximum 測定値および計算値 10 g -
Additional parameter details

The SAR value was measured without casing and electrode cap.

測定および計算の詳細

The SAR was determined in keeping with CENELEC by means of a spherical liquid filled phantom, 20 cm in diameter, with the phone at a distance of 5 mm. The measurement was performed at the max. absorbed power location (hot spot) using a 3D guided calibrated probe terminating in three perpendicular dipoles.

ばく露を受けた生物:

方法 影響評価項目／測定パラメータ／方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中
  • ばく露後

研究の主なアウトカム（著者による）

There were no alterations of the EEG recorded after the mobile phone exposure. The reaction time was shortened by 20 ms in response to all target stimuli. The mobile phone field might effectively inhibit the excessive sleepiness which is assumed to be, in narcolepsy, an active process. This may correspond with evidence of improved performance while solving monotonous cognitive task requiring sustained attention. With regard to the fact that the subjects of the group were exclusively patients with narcolepsy, it is difficult to decide whether the mobile phone exposure's positive effect on visual event-related potential was due to the narcoleptics' enhanced sensibility or whether this was the result of the general effects of a high frequency electromagnetic field associated with the given type of cognitive task.

研究の種別:

研究助成

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