Study type: Medical/biological study (experimental study)

Teratological evaluation of mouse fetuses exposed to a 20 kHz EMF. med./bio.

Published in: Bioelectromagnetics 2009; 30 (4): 330-333

Aim of study (acc. to author)

To evaluate the inportance of gestational age of pregnant mice with regard to the exposure of 20 kHz electromagnetic field on embryogenesis.

Background/further details

In a previous study (publication 10485 ) with 6.26 µT (limit value for general population), the authors did not find an effect on the fetal development of pregnant mice.
In this study, the intensity was increased up to 30 µT (limit value for occupational exposure). Pregnant mice were exposed (n=10) and sham exposed (n=11) from gestation day 2.5-15.5. On gestation day 18, the dams were sacrificed.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 20 kHz
Exposure duration: 8 h/day from day 2.5 to day 15.5 of gestation

Exposure 1

Main characteristics
Frequency 20 kHz
Type
Exposure duration 8 h/day from day 2.5 to day 15.5 of gestation
Exposure setup
Exposure source
Setup horizontal coils consisting of 1.2 mm enamel-coated copper wire for whole body exposure
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 30 µT peak value measured - -

Reference articles

  • Kim SH et al. (2004): Teratological studies of prenatal exposure of mice to a 20 kHz sawtooth magnetic field.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No significant effects of exposure on the developmental stage of the fetuses in pregnant mice were found. No difference was observed for the sex ratio between exposed and sham exposed mice.
Electromagnetic field exposure in pregnant mice did not affect fetal external and internal development. Thus, the data confirm the findings from a previous study (publication 10485).

Study character:

Study funded by

Related articles