Study type: Medical/biological study (experimental study)

No evidence of cellular alterations by MilliTesla-level static and 50 Hz magnetic fields on S. cerevisiae. med./bio.

Published in: Electromagn Biol Med 2010; 29 (4): 154-164

Aim of study (acc. to author)

Alterations in cell survival, cell cycle, colony forming ability, and mutation frequency in the yeast Saccharomyces cerevisiae were studied to assess the effects of short-term (1 h) and long-term (72 h) exposures to static magnetic fields or 50 Hz sinusoidal homogeneous magnetic field.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
Exposure duration: continuous for 1 h or 72 h
Exposure 2: 50 Hz
Exposure duration: continuous for 1 h or 72 h

Exposure 1

Main characteristics
Frequency
Type
Exposure duration continuous for 1 h or 72 h
Exposure setup
Exposure source
Setup pair of Helmholtz coils with a diameter of 40 cm and 154 turns of 1.4 mm copper wire, mounted 20 cm apart on a wooden frame; Ependorf tubes with the yeast placed in the center of the coil system; vertical field homogeneity higher than +/- 3 %
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.35 mT minimum measured - -
magnetic flux density 1.4 mT - measured - -
magnetic flux density 2.45 mT maximum measured - -

Exposure 2

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuous for 1 h or 72 h
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.35 mT minimum measured - -
magnetic flux density 1.4 mT - measured - -
magnetic flux density 2.45 mT maximum measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data showed that short-term (1 h) and long-term (72 h) exposures to 0.35 mT, 1.4 mT, and 2.45 mT static magnetic fields or sinusoidal 50 Hz magnetic fields did not induce alterations in cell survival, cell cycle, colony forming ability, and mutation frequency of the yeast Saccharomyces cerevisiae.

Study character:

Study funded by

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