Study type: Medical/biological study (experimental study)

The prophylactic effect of vitamin C on oxidative stress indexes in rat eyes following exposure to radiofrequency wave generated by a BTS antenna model. med./bio.

Published in: Int J Radiat Biol 2013; 89 (2): 128-131

Aim of study (acc. to author)

To evaluate the possible effect of exposure to an electromagnetic field on oxidative stress in the eye of rats and the prophylactic effect of vitamin C.

Background/further details

32 male rats were divided into four groups: 1.) control group, 2.) vitamin C administration, 3.) exposure and 4.) exposure + vitamin C administration (each group n=8).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: continuous for 4 h/day on 45 days

General information

Animals were divided into the following four groups: i) control ii) treated with vitamin C (200 mg/kg body weight) iii) exposure to EMF iv) treated with vitamin C (200 mg/kg body weight ) + exposure to EMF

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continuous for 4 h/day on 45 days
Exposure setup
Exposure source
Distance between exposed object and exposure source 5 m
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 0.6789 mW/cm² - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In exposed samples, the enzyme activities of superoxide dismutase, glutathione peroxidase and catalase were significantly decreased in comparison to the control group, while an administration of vitamin C increased these enzyme activities and brought them to normal levels with no significant differences compared to the control group. Additionally, in exposed rats, the concentration of malondialdehyde was significantly increased in comparison to the control. An administration of vitamin C prevented these effects.
The authors conclude that exposure to an electromagnetic field led to oxidative stress in the eye tissue and that vitamin C could prevent it.

Study character:

Study funded by

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