66 rats were divided into three groups (n=22 per group): 1.) exposure group, 2.) exposure + garlic administration (500 mg/kg/d) and 3.) control group. At the end of the study, blood and brain tissues were collected.
|Exposure duration||continuous for 1 h/day during 3 weeks|
|Modulation type||cf. additional info|
No differences among the groups with regard to the malondialdehyde levels in serum and brain tissue were detected. Although the serum "advanced oxidation protein products" levels did not differ among the groups, the "advanced oxidation protein products" levels in the brain homogenates of the exposed group were higher than those of the control group. In the exposed group with garlic administration, there was a statistically significant decrease in the "advanced oxidation protein products" levels compared to the exposed group. There was no statistically significant difference between the control group and the exposed group with garlic administration. The serum nitric oxide levels increased significantly in the exposed group and in the exposed group with garlic administration compared with the control group. However, there was no difference between the exposed group and the exposed group with garlic administration regarding the serum nitric oxide levels. No differences were found in the serum levels of paraoxonase among the groups. No paraoxonase was found in the brain homogenates.
The authors summarize that the exposure to a radiofrequency electromagnetic field at 1.8 GHz did not cause lipid peroxidation and nitric oxide increase but led to protein oxidation in the brain tissue and an increase in serum nitric oxide level. Furthermore, an administration of garlic reduced the protein oxidation in the brain tissue but did not have any effects on serum nitric oxide levels.