Study type: Medical/biological study (experimental study)

Effects of mobile phone use on brain tissue from the rat and a possible protective role of vitamin C - a preliminary study. med./bio.

Published in: Int J Radiat Biol 2010; 86 (12): 1044-1049

Aim of study (acc. to author)

To study the effects of mobile phone exposure on brain tissue and a possible protective role of vitamin C.

Background/further details

40 female rats were divided into four groups (each group n=10): 1) control group, 2) mobile phone exposure group, 3) "mobile phone exposure plus vitamin C" group and, 4) vitamin C treatment group.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: 4 weeks - mobile phone in stand-by mode, called four times a day for 10 min.
  • SAR: 0.95 W/kg

General information

animals were divided into four groups: i) control ii) mobile phone iii) mobile phone + 25mg/kg vitamin C daily iv) 25mg/kg vitamin C daily

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration 4 weeks - mobile phone in stand-by mode, called four times a day for 10 min.
Exposure setup
Exposure source
Distance between exposed object and exposure source 10 cm
Setup mobile phone placed above the cages
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.95 W/kg - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Mobile phone exposure caused an inhibition in 5'-nucleotidase and catalase enzyme activities as compared with the control group. Glutathione peroxidase enzyme activity and the malondialdehyde level were also reduced in the mobile phone group but not significantly.
Vitamin C caused a significant increase in the enzyme activity of glutathione peroxidase and non-significant increase in the enzyme activities of 5'-nucleotidase, adenosine deaminase and catalase.
The data suggest that vitamin C may play a protective role against detrimental effects of mobile phone irradiation in brain tissue.

Study character:

Study funded by

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