Study type: Medical/biological study (experimental study)

Protective role of sesame oil against mobile base station-induced oxidative stress. med./bio.

Published in: J Radiat Res Appl Sci 2014; 7 (1): 1-6

Aim of study (acc. to author)

The effects of exposure of rats to a 900 MHz electromagnetic field on blood parameters and the possible protective role of sesame oil (antioxidant) against oxidative stress should be investigated.

Background/further details

Rats were divided into the following groups (n=8 each): 1) exposure to the electromagnetic field, 2) exposure and administration of 1.5 ml sesame oil, 3) exposure and administration of 3 ml sesame oil, 4) control group. Groups 2 and 3 received the sesame oil orally three times a week.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: continuous for 24 h/day for 8 weeks

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continuous for 24 h/day for 8 weeks
Exposure setup
Exposure source
Distance between exposed object and exposure source 8 m
Chamber plastic cages
Setup base station was constructed on the roof of a building
Parameters
Measurand Value Type Method Mass Remarks
power density 0.5 mW/cm² - measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The level of testosterone was significantly increased in all exposure groups (groups 1-3) and the level of triglycerides was significantly increased in both exposure groups with sesame oil (groups 2 and 3) compared to the control group.
The superoxide dismutase and catalase enzyme activities were significantly reduced in exposed rats without sesame oil (group 1) and they were significantly increased in exposed rats with sesame oil (partly in group 2, consistently in group 3) compared to the control group.
The total cholesterol level was significantly reduced and the glutathione reductase enzyme activity was significantly increased in group 3 compared to the control group.
HDL and LDL cholesterol showed contrary trends: HDL cholesterol was significantly reduced in group 1 compared to the control group and groups 2 and 3 showed significantly increased values compared to group 1. LDL cholesterol was significantly increased in group 1 compared to the control group and groups 2 and 3 showed significantly reduced values compared to group 1.
The authors conclude that exposure of rats to a 900 MHz electromagnetic field might influence blood parameters and induce oxidative stress and that sesame oil as an antioxidant might attenuate these effects.

Study character:

Study funded by

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