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The effects of exposure of rats to a 900 MHz electromagnetic field on blood parameters and the possible protective role of sesame oil (antioxidant) against oxidative stress should be investigated.
Rats were divided into the following groups (n=8 each): 1) exposure to the electromagnetic field, 2) exposure and administration of 1.5 ml sesame oil, 3) exposure and administration of 3 ml sesame oil, 4) control group. Groups 2 and 3 received the sesame oil orally three times a week.
ばく露 | パラメータ |
---|---|
ばく露1:
900 MHz
ばく露時間:
continuous for 24 h/day for 8 weeks
|
|
周波数 | 900 MHz |
---|---|
タイプ |
|
ばく露時間 | continuous for 24 h/day for 8 weeks |
ばく露の発生源/構造 |
|
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Distance between exposed object and exposure source | 8 m |
チャンバの詳細 | plastic cages |
ばく露装置の詳細 | base station was constructed on the roof of a building |
測定量 | 値 | 種別 | Method | Mass | 備考 |
---|---|---|---|---|---|
電力密度 | 0.5 mW/cm² | - | 測定値 | - | - |
The level of testosterone was significantly increased in all exposure groups (groups 1-3) and the level of triglycerides was significantly increased in both exposure groups with sesame oil (groups 2 and 3) compared to the control group.
The superoxide dismutase and catalase enzyme activities were significantly reduced in exposed rats without sesame oil (group 1) and they were significantly increased in exposed rats with sesame oil (partly in group 2, consistently in group 3) compared to the control group.
The total cholesterol level was significantly reduced and the glutathione reductase enzyme activity was significantly increased in group 3 compared to the control group.
HDL and LDL cholesterol showed contrary trends: HDL cholesterol was significantly reduced in group 1 compared to the control group and groups 2 and 3 showed significantly increased values compared to group 1. LDL cholesterol was significantly increased in group 1 compared to the control group and groups 2 and 3 showed significantly reduced values compared to group 1.
The authors conclude that exposure of rats to a 900 MHz electromagnetic field might influence blood parameters and induce oxidative stress and that sesame oil as an antioxidant might attenuate these effects.
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