Study type: Medical/biological study (experimental study)

The impact of electromagnetic field at a frequency of 50 Hz and a magnetic induction of 2.5 mT on viability of pineal cells in vitro. med./bio.

Published in: J Biol Regul Homeost Agents 2016; 30 (4): 1067-1072

Aim of study (acc. to author)

The effects of exposure of pig pinealocytes to a 50 Hz magnetic field on cell viability should be investigated.

Background/further details

The pinealocytes were divided into the following groups: exposure to the magnetic field for 1) 1 hour, 2) 2 hours, 3) 3 hours, 4) 3 hours per day for 2 days and 5) 3 hours per day for 3 days, 6) control group.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: 1 hour
Exposure 2: 50 Hz
Exposure duration: 2 hours
Exposure 3: 50 Hz
Exposure duration: 3 hours
Exposure 4: 50 Hz
Exposure duration: 3 hours/day for 2 days
Exposure 5: 50 Hz
Exposure duration: 3 hours/day for 3 days

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration 1 hour
Exposure setup
Exposure source
  • not specified
Chamber 96-well plate
Setup Astar generator (Magneris, Astar)
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2.5 mT - - - -

Exposure 2

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration 2 hours
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2.5 mT - - - -

Exposure 3

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration 3 hours
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2.5 mT - - - -

Exposure 4

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration 3 hours/day for 2 days
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2.5 mT - - - -

Exposure 5

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration 3 hours/day for 3 days
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2.5 mT - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Exposure to the magnetic field for 2 hours (group 2) and 3 hours (group 3) led to a significant increase in cell viability compared to the control group, while exposure for 3 hours per day for 3 days (group 5) resulted in a significant decrease in cell viability compared to the control group.
The authors conclude that exposure of pig pinealocytes to a 50 Hz magnetic field might have exposure duration-dependent effects on cell viability.

Study character:

Study funded by

Related articles