Male rats were divided into the following groups (n=8 each): 1) exposure to the electromagnetic field, 2) co-exposure to the electromagnetic field and melatonin, 3) sham exposure and treatment with saline solution. Melatonin (100 μg/kg body weight) or the saline solution were injected subcutaneously immediately before daily exposure. Subsequently, all animals were anesthetized, (sham) exposed and killed at the end of the exposure period.
|Exposure duration||continuous for 30 min/day for 10 days|
|Setup||exposure system consisted of a plastic tube (length: 12 cm, diameter: 5.5 cm) and a dipole antenna; rats were placed in the tube and positioned in close contact above the dipole antenna and the tube was ventilated from head to tail the reduce stress for the rat|
|Sham exposure||A sham exposure was conducted.|
In the electromagnetic field exposure group (group 1), a significant decrease in enzyme activities of all antioxidant enzymes (superoxide dismutase, glutathione peroxidase and catalase) was found in hippocampal samples compared to the sham exposure group, while the lipid peroxidation was higher (no significance stated). Co-exposure to the electromagnetic field and melatonin (group 2) increased enzyme activities of antioxidant enzymes (no significance stated) and significantly reduced lipid peroxidation compared to group 1. (Remark EMF-Portal: These are the results as described in the flow text. The text refers also to tables and figures which can not be found in the article.)
The authors conclude that exposure of rats to a 900 MHz electromagnetic field might induce oxidative stress in the brain and that melatonin might have a protective effect.