Study type: Medical/biological study (experimental study)

Effect of mobile phone exposure on apoptotic glial cells and status of oxidative stress in rat brain med./bio.

Published in: Electromagn Biol Med 2009; 28 (4): 342-354

Aim of study (acc. to author)

To study the effects of mobile phone exposure on glial cells in rat brain.

Background/further details

31 adult male rats were divided into three groups: 1) Exposure group (n=14), 2) sham exposure group (n=7) and 3) cage control group (n=10).



Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: continuous for 2 hr/day, 7 days/week for 10 months

Exposure 1

Main characteristics
Frequency 900 MHz
Exposure duration continuous for 2 hr/day, 7 days/week for 10 months
Exposure setup
Exposure source
  • GSM Simulator 900PM10
Distance between exposed object and exposure source 1 cm
Setup rats placed in a Plexiglas carousel with their heads positioned around the generator's antenna
Sham exposure A sham exposure was conducted.
Measurand Value Type Method Mass Remarks
electric field strength 16.26 V/m minimum measured - -
electric field strength 29.43 V/m maximum measured - -
SAR 0.17 W/kg minimum calculated brain -
SAR 0.58 W/kg maximum calculated brain -
power density 0.052 mW/cm² minimum measured - around the brain
power density 0.338 mW/cm² maximum measured - around the brain

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data showed that apoptosis was significantly reduced in the exposed group compared to the sham exposure and the cage control groups. The p53 status was not significantly changed by the exposure. The total antioxidant capacity and catalase activity were increased in the exposed group compared to sham exposure group. In terms of the total oxidant status and oxidative stress index, there was no statistically significant difference between exposure and control groups.
The authors conclude that apoptosis, total antioxidant capacity and catalase enzyme activity in rat brain might be altered by 900 MHz exposure.

Study character:

Study funded by

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