Study type: Medical/biological study (experimental study)

The effect of radiofrequency radiation on DNA and lipid damage in non-pregnant and pregnant rabbits and their newborns. med./bio.

Published in: Gen Physiol Biophys 2010; 29 (1): 59-66

Aim of study (acc. to author)

To study the possible biological effects of GSM-like radiofrequency whole body exposure on brain oxidative DNA damage and lipid peroxidation both in non-pregnant and pregnant rabbits and in their newborns.

Background/further details

36 rabbits were divided into four groups: 1) non-pregnant control group (n=9), 2) non-pregnant, radiofrequency exposed group (n=9), 3) pregnant control group (n=9) and 4) pregnant, radiofrequency exposed group (n=9). Newborns (n=18; one of each litter) were also divided into two groups: newborns of control group (n=9) and newborns of exposed group (n=9).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 1,800 MHz
Modulation type: pulsed
Exposure duration: continuous for 15 min/day on 7 days - from day 15 to day 22 of gestation

General information

rabbits were treated in four groups: i) non-pregnant control ii) non-pregnant EMF exposure iii) pregnant control iv) pregnant EMF exposure

Exposure 1

Main characteristics
Frequency 1,800 MHz
Type
Exposure duration continuous for 15 min/day on 7 days - from day 15 to day 22 of gestation
Modulation
Modulation type pulsed
Pulse width 576 µs
Duty cycle 12.5 %
Repetition frequency 217 Hz
Pulse type rectangular
Additional info

GSM-like signal

Exposure setup
Exposure source
Chamber shielded room
Setup antenna placed above the rabbit's Plexiglas cage (one animal per cage)
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 14 V/m - measured - +/- 0.5 V/m
power 0.1 W - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Malondialdehyde and 8-hydroxy-2-deoxyguanosine levels of non-pregnant and pregnant radiofrequency exposed animals significantly increased compared with not-exposed controls. No differences were found in the newborns.
The authors conclude, that 1800 MHz GSM-like radiofrequency exposure of non-pregnant and pregnant rabbits for seven days resulted in the release of secondary messengers, such as free radicals, leading to oxidative destruction in lipids and DNA.

Study character:

Study funded by

Related articles