Study type: Medical/biological study (experimental study)

Oxidative stress effects on the central nervous system of rats after acute exposure to ultra high frequency electromagnetic fields med./bio.

Published in: Bioelectromagnetics 2006; 27 (6): 487-493

Aim of study (acc. to author)

To study the effect of acute ultrahigh frequency electromagnetic field exposure on non-enzymatic antioxidant defense and lipid and protein oxidative damage in the rat frontal cortex and hippocampus.

Background/further details

A total of 31 rats were divided by age into three groups (30, 80, and 210 days) and exposed.



Exposure Parameters
Exposure 1: 834 MHz
Exposure duration: repeated daily exposure, 7.5 h per day, for 6 days

Exposure 1

Main characteristics
Frequency 834 MHz
Exposure duration repeated daily exposure, 7.5 h per day, for 6 days
Additional info vertical polarisation
Modulation type unspecified
Exposure setup
Exposure source
Distance between exposed object and exposure source 20 cm
Chamber The animal exposure cage (total diameter 93 cm, height 33 cm in the center and 24 cm at the periphery) was divided into four compartments (1276.27 cm² each) placed around an inner compartment (1256.64 cm², r = 20 cm) and was made of wood (floor and inner walls) and transparent plastic (lining the floor and outer wall) covered by a galvanised steel net (1.5 x 1.5 cm mesh).
Setup The mobile phone was positioned in the center of the middle compartment, and the extremity of the antenna was in contact with the floor. The animals were placed in one of the compartments, and their distance from the antenna varied from 20 to 45 cm.
Sham exposure A sham exposure was conducted.
Additional info The sham exposure cage was placed 40.5 cm away from the real exposure cage.
Measurand Value Type Method Mass Remarks
power 600 mW peak value - - -
electric field strength 35.7 V/m effective value measured - 23-35.7 V/m
magnetic field strength 90 mA/m - measured - 65-90 mA/m
power density 0.35 mW/cm² mean measured - 0.15-0.35 mW/cm²
SAR 0.98 W/kg - calculated - 0.41-0.98 W/kg for 30 days old rats
SAR 0.86 W/kg - calculated - 0.36-0.86 W/kg for 70 days old rats

Reference articles

  • Peyman A et al. (2001): Changes in the dielectric properties of rat tissue as a function of age at microwave frequencies

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No changes in lipid and protein damage, and also in non-enzymatic antioxidant defense were found in frontal cortex or hippocampus. These data indicate that acute ultrahigh frequency electromagnetic field exposure is not able to produce detectable oxidative stress in rats from any age tested.

Study character:

Study funded by

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