研究のタイプ: 医学/生物学の研究 (experimental study, theoretical study)

[弱い磁界問題への新しいアプローチ:生きている対象への影響] med./bio.

A new approach to the problem of weak magnetic fields: an effect on living objects.

掲載誌: Dokl Biochem Biophys 2003; 392: 274-278
Journal partially peer-reviewed/peer-review process unclear

この研究は、単純な生物の特定の物理的特性(生細胞の生物発光強度、赤血球沈降速度、および水生生物の運動能)に対する生物体外の磁気ベクトルポテンシャルの影響を調べた。また、水溶液中の単純な化学反応の速度に対する磁気ベクトルポテンシャルの影響も調べた。培養器内で、円筒形の永久磁石2個の間隙に試料を入れたガラス管を置いてばく露を行った。実験に応じて、磁束密度は1 mTおよび2 mT、ばく露時間は1時間、2時間、3.5時間連続とした。擬似ばく露群は、同じ培養装置内で、磁石対を覆う円筒形の磁気シールドの外側に十分に距離をとって置かれた。その結果、細菌生物発光は、1時間ばく露により抑制された;この所見は、2時間の観察期間中も持続した;赤血球沈降反応パラメータは、ばく露群でも正常範囲であったが、磁界の強さへの依存性が、個別的かつ非線形的に見られた;水生生物の運動能は1時間ばく露で変化しなかった;水溶液中のハイドロキノン酸化反応については、対照群に比べて、ばく露群の吸収スペクトルにほとんど違いはなかったが、ばく露前後での吸収スペクトル差は有意に変化した、と報告している。

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研究目的(著者による)

To focus attention on the well-known concept of magnetic vector potential. The aim of this study was to describe the findings of the effects of external vector potential on certain physical characteristics of simple living objects: the intensity of bioluminescence of living cells, the rate of erythrocyte sedimentation, and the mobility of hydrobionts. The effects of external vector potential on the rate of a simple chemical reaction in aqueous solution were also investigated.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1:
  • DC/static
ばく露時間: continuous for 1 h
-
ばく露2:
  • DC/static
ばく露時間: continuous for 1 h
ばく露3:
  • DC/static
ばく露時間: continuous for 1 h
ばく露4:
  • DC/static
ばく露時間: continuous for 1 h to 3.5 h
-

ばく露1

主たる特性
周波数
  • DC/static
タイプ
  • magnetic field
ばく露時間 continuous for 1 h
Additional information Vector potential field was applied
ばく露装置
ばく露の発生源/構造
  • two cylindrical permanent samarium-cobalt magnets
ばく露装置の詳細 Five tubes containing water suspension of bacteria was incubated at a distance of 5 cm from the source
Additional information Test tubes with identical suspension serving as contol were incubated for 1 h at a distance of more than 1 m from the exposure tubes The stray field was attenuated using a closed cylindrical steel shield (12 cm high, 1 cm cell wall) which surrounded the magnetic circuit
パラメータ

No parameters are specified for this exposure.

ばく露2

主たる特性
周波数
  • DC/static
タイプ
  • magnetic field
ばく露時間 continuous for 1 h
Additional information Static magnetic field + vector potential field were applied
ばく露装置
ばく露の発生源/構造
  • two cylindrical permanent samarium-cobalt magnets
Additional information Blood stabilized with sodium citrate was kept in several pipettes, one of which was exposed to a source of vector potential field at a range of 3 cm
パラメータ
測定量 種別 Method Mass 備考
磁束密度 1 mT unspecified 測定値 - -

ばく露3

主たる特性
周波数
  • DC/static
タイプ
  • magnetic field
ばく露時間 continuous for 1 h
Additional information Static magnetic field and vector potential field were applied
ばく露装置
ばく露の発生源/構造
  • two cylindrical permanent samarium-cobalt magnets
ばく露装置の詳細 Petri dishes containing spirostoma and water were located at a distance 5 cm from the source.
Additional information Dishes with identical suspension serving as contol were placed at a distance of more than 1 m from the exposure dishes
パラメータ
測定量 種別 Method Mass 備考
磁束密度 2 mT unspecified 測定値 - -

ばく露4

主たる特性
周波数
  • DC/static
タイプ
  • magnetic field
ばく露時間 continuous for 1 h to 3.5 h
Additional information Vector potential field was applied
ばく露装置
ばく露の発生源/構造
  • two cylindrical permanent samarium-cobalt magnets
ばく露装置の詳細 One cuvette was located at a distance 5 cm from the source along the device axis and another was exposed at a distance of 15 m from the source. Both cuvettes were under the same wooden housing
Additional information Dishes with identical suspension serving as contol were placed at a distance of more than 1 m from the exposure dishes
パラメータ

No parameters are specified for this exposure.

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

Bacterial luminescence: 1 h exposure to vector potential exerted a distinct effect of bioluminescence suppression. The findings of exposure were retained during 2 h of observation.
Erythrocyte sedimentation: Exposure to vector potential field exerted a normalizing effect on the erythrocyte sedimentation reaction parameters. The dependence of the strength of the effect was individual and nonlinear.
Motor activity of hydrobionts: After 1 h of exposure the value of motor activity index in the control group remained virtually unchanged, whereas the value of motor activity index in the experimental group decreased.
Reaction of hydroquinone oxidation in solution: There was almost no difference between the absorption spectra of the controls, whereas the differential-mode absorption spectrum of exposed samples changed significantly.
The findings can be regarded as evidence of the effect exerted by vector potential on elementary processes.

研究の種別:

研究助成