研究のタイプ: 医学/生物学の研究 (experimental study)

[9.3 GHzマイクロ波ばく露を受けたラットの体温調節反応:EとHの向きによる比較] med./bio.

Thermoregulatory responses of rats exposed to 9.3-GHz microwaves: a comparison of E and H orientation.

掲載誌: Physiol Chem Phys Med NMR 1992; 24 (1): 1-10

この研究は、9.3GHz高周波電磁界放射(RFR)連続波遠方界ばく露ケタミン麻酔したラットに与え、体温、心臓血管系および呼吸の変化への影響が電界および磁界(EおよびH)の方向により変わるか否かを調べた。1℃の結腸温度変化(38. 5℃から39.5℃へ)を生じさせるために、SAR= 12.5W / kg(EおよびHの両方向)、電力密度79 mW / cm 2(E方向)および59mW / cm 2(H方向)の照射を行った。実験中、動脈血圧呼吸数結腸温(Tc)鼓膜温(Tt)左右皮下温(TslおよびTsr)(RFR源に向かう側および離れた側)および尾部温(Tta)が連続的に記録された。その結果、E方向ばく露中のTsr変化は、Tc変化よりもかなり小さかった;H方向ばく露中のTtおよびTsr変化はTc上昇に近似した;両方向ばく露中は、TslとTtaの変化はTc上昇よりもかなり大きかった、などの知見を報告している。

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研究目的(著者による)

The aim of this study was to determine the effects of exposure orientation relative to electric and magnetic fields (E (long axis of body parallel to electric field)- and H (long axis of body parallel to magnetic field)-orientation) on the thermal, cardiovascular, and respiratory changes in anesthetized rats exposed to continuous wave 9.3 GHz radiofrequency irradiation.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 9.3 GHz
Modulation type: CW
ばく露時間: intermittent*
ばく露2: 9.3 GHz
Modulation type: CW
ばく露時間: intermittent*
  • SAR: 12.5 mW/g mean (whole body)
  • 電力密度: 590 W/m² unspecified (H orientation.)

General information

*The exposure was discontinued when the colonic temperature increased to 39.5°C and it was initiated again when the temperature returned to 38.5°C. This procedure was continued for 3 cycles.

ばく露1

主たる特性
周波数 9.3 GHz
タイプ
  • electromagnetic field
特性
  • far field
偏波
  • linear
ばく露時間 intermittent*
Additional information Animals were exposed in E-orientation (long axis parallel to electric field)
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
Distance between exposed object and exposure source 1.5 m
チャンバの詳細 Eccosorb RF-shielded anechoic chamber
ばく露装置の詳細 Rats placed on a holder
Additional information The holder consisted of seven 0.5 cm (O.D) Plexiglas rods mounted in a semicircular pattern on 4 cm x 6 cm Plexiglas plates (0.5 cm thick). Colonic rise and recovery time were 15.2 ± 0.8 min and 24.4 ± 1.3 min respectively.
パラメータ
測定量 種別 Method Mass 備考
電力密度 790 W/m² unspecified 測定値 - -
SAR 12.5 mW/g mean - whole body -

ばく露2

主たる特性
周波数 9.3 GHz
タイプ
  • electromagnetic field
特性
  • far field
偏波
  • linear
ばく露時間 intermittent*
Additional information Animals were exposed in H-orientation (long axis parallel to magnetic field)
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
Distance between exposed object and exposure source 1.5 m
Additional information Colonic rise and recovery time were 15.0 ± 0.9 min and 26.0 ± 2.3 min respectively.
パラメータ
測定量 種別 Method Mass 備考
SAR 12.5 mW/g mean - whole body -
電力密度 590 W/m² unspecified 測定値 - H orientation.

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中

研究の主なアウトカム(著者による)

The right subcutaneous temperature change during E-orientation irradiation was considerably less than the colonic temperature change. The tympanic temperature and right subcutaneous temperature (H-orientation) alterations approximated the colonic temperature increase. The subcutaneous left temperature and tail temperature changes (both orientations) were considerably greater than the colonic temperature increase. The tympanic temperature and subcutaneous left temperature increases were virtually equal under the two irradiation conditions; however, the subcutaneous right temperature increase was significantly greater during H-orientation exposure, and the tail temperature increase was significantly greater during E-orientation irradiation.
Heart rate and mean arterial pressure increased significantly during exposure; however the cardiovascular responses were not affected by irradiation orientation.

研究の種別:

研究助成

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