Study type: Medical/biological study (experimental study)

Effects of mobile phone radiation on reproduction and development in Drosophila melanogaster med./bio.

Published in: J Cell Biochem 2003; 89 (1): 48-55

Aim of study (acc. to author)

To study the effects of a radiofrequency signal produced by a GSM multiband mobile phone on Drosophila melanogaster, during the 10-day developmental period from egg laying through pupation.

Background/further details

The investigated serum response element (SRE) is a regulatory sequence required for a specific activation of the cellular immediate early genes, c-fos and c-jun.



Exposure Parameters
Exposure 1: 1,900 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 2 times 60 min with a 4-h interval, for 10 days

Exposure 1

Main characteristics
Frequency 1,900 MHz
Exposure duration repeated daily exposure, 2 times 60 min with a 4-h interval, for 10 days
Modulation type pulsed
Exposure setup
Exposure source
Chamber Flies were placed into 50-ml cylindrical glass vials (2.5 cm diameter and 10 cm height), with standard food 1 cm thick at the bottom of the vials.
Setup Five vials were placed parallel to the antenna of a GSM phone either with power off, or active, or active with an MP12 device attached.
Sham exposure A sham exposure was conducted.
Additional info The model MP12 commercial "Mitigation Device" was a "magnetic oscillator 0.8/0.9 GHz/1.8/1.9 GHz". According to the manufacturer, the frequency range is measurable by SQUID only. The main frequencies observed in ELF were 10/12 Hz and 40/45 Hz, and the intensity of the magnetic field was 100/150 Femto-Tesla. Non-phospho-ELK-1 served as a positive control.
Measurand Value Type Method Mass Remarks
SAR 1.4 W/kg unspecified cf. remarks cf. remarks determined by the manufacturer for a human head
electric field strength 2.2 V/m effective value measured - 1.3-2.2 V/m at the antenna
electric field strength 3.3 V/m effective value measured - 1.9-3.3 V/m at the speaker

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The non-thermal irradiation from the GSM mobile phone increased numbers of offspring, elevated HSP70 levels, increased serum response element DNA-binding and induced the phosphorylation of the nuclear transcription factor, ELK-1.

Study character:

Study funded by

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