Study type: Medical/biological study (experimental study)

Neonatal mouse brain exposure to mobile telephony and effect on blood-brain barrier permeability. med./bio.

Published in: Pathology 2006; 38 (3): 262-263

Aim of study (acc. to author)

To study the effect of mobile telephone exposure on blood-brain barrier permeability in the brain of neonatal mice.

Background/further details

A positive control group with cadmium-induced blood-brain barrier damage was also included.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 60 min/day, for 7 days
  • SAR: 4 W/kg average over mass (whole body)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Charakteristic
Exposure duration repeated daily exposure, 60 min/day, for 7 days
Modulation
Modulation type pulsed
Pulse width 0.6 ms
Repetition frequency 217 Hz
Additional info

similar to GSM

Exposure setup
Exposure source
Setup The exposure system consisted of a cylindrical parallel plate with mice restrained motionless in clear Perspex tubes arranged radially around the antenna [Finnie et al., 2001].
Sham exposure A sham exposure was conducted.
Additional info A non-exposed, freely moving, cage control group without handling was also included.
Parameters
Measurand Value Type Method Mass Remarks
SAR 4 W/kg average over mass unspecified whole body -

Reference articles

  • Finnie JW et al. (2001): Effect of global system for mobile communication (gsm)-like radiofrequency fields on vascular permeability in mouse brain.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No albumin extravasation was found in brains of exposed or control (sham exposed and freely moving caged) mice. By contrast, in the positive control mice there was substantial albumin extravasation.
It appears that exposure of the developing mouse brain to mobile phone-type radiofrequency electromagnetic fields does not produce any perturbations of blood-brain barrier integrity.

Study character:

Study funded by

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