Study type: Medical/biological study (experimental study)

Effect of mobile telephony on blood-brain barrier permeability in the fetal mouse brain. med./bio.

Published in: Pathology 2006; 38 (1): 63-65

Aim of study (acc. to author)

To study the effect of mobile telephone exposure on blood-brain barrier permeability in the immature brain of mice.

Background/further details

Pregnant mice were exposed from day 1 to day 19 of gestation and immediately prior to parturition on gestational day 19, fetal heads were collected. A positive control group with cadmium-induced blood-brain barrier damage was also included.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure for 60 min/day from day 1 to day 19 of gestation
  • SAR: 4 W/kg average over mass (whole body)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Charakteristic
Exposure duration repeated daily exposure for 60 min/day from day 1 to day 19 of gestation
Modulation
Modulation type pulsed
Pulse width 0.6 ms
Repetition frequency 217 Hz
Exposure setup
Exposure source
Setup The exposure system consisted of a cylindrical parallel plate with mice restrained in clear Perspex tubes, preventing them from changing their orientation, and arranged radially around the dipole antenna. A forced air supply was maintained through the cylinders to ensure no heat build-up, and there was no rise in core body temperature.
Additional info Pregnant control mice were sham-exposed or freely moving in a cage. A positive control group obtained cadmium-induced BBB damage.
Parameters
Measurand Value Type Method Mass Remarks
SAR 4 W/kg average over mass - whole body -

Reference articles

  • Finnie JW et al. (2001): Effect of global system for mobile communication (gsm)-like radiofrequency fields on vascular permeability in mouse brain.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No albumin extravasation was found in brains of exposed or control mice.

Study character:

Study funded by

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