Five groups of mice were examined (n=10 per group): 1.) sham exposure, 2.) exposure, 3.) exposure + 30 mg/kg LSPC, 4.) exposure + 60 mg/kg LSPC and 5.) exposure + 90 mg/kg LSPC. The LSPCs were derived from the seedpod of lotus plants and administered orally. Procyanidins belong to the class of flavonoids and are widely distributed in fruits, vegetables, seeds, flowers and bark. They act as an antioxidant.
mice were exposed in well ventilated perspex boxes and these boxes were placed in the middle of the coils, temperature in the boxes was 23 ± 0.5°C, pair of helmholtz coils (1 mm wire diameter, 32 cm internal diameter, 36 cm external diameter) with 500 turns was used
exposure device was placed in a temperature controlled room (23 ± 2°C)
The Priority Academic Program Development of Jiangsu Higher Education Institutions, China
Major Scientific and Technological Special Project for "Significant New Drugs Creation", China
Zhang H et al.
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