Study type: Medical/biological study (experimental study)

Evaluation of the effects of mobile phones on the neural tube development of chick embryos. med./bio.

Published in: Turk Neurosurg 2013; 23 (6): 742-752

Aim of study (acc. to author)

To investigate the effects of exposure to mobile phones on the developing neural tissue of chicken embryos.

Background/further details

Fertilized eggs were divided into 4 groups (n=50 per group): 1.) no exposure, 2.) exposed to a mobile phone in the "standby mode", 3.) exposed to a mobile phone in the "calling mode" and 4.) exposed to a mobile phone in the "talking mode". Eggs were opened and examined after 30, 48 or 72 hours.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
  • unspecified
Exposure duration: standby mode for 30, 48 or 72 hours
-
Exposure 2:
  • unspecified
Exposure duration: calling mode for 30, 48 or 72 hours (mobile phone was called every 30 minutes for 10 seconds)
  • SAR: 0.77 W/kg
Exposure 3:
  • unspecified
Exposure duration: talking mode for 30, 48 or 72 hours (mobile phone was kept in talking mode for 10 minutes every hour)
  • SAR: 0.77 W/kg

Exposure 1

Main characteristics
Frequency
  • unspecified
Type
Exposure duration standby mode for 30, 48 or 72 hours
Exposure setup
Exposure source
Setup mobile phone was placed in the center of the incubator with a distance of < 25 cm between mobile phone and eggs; eggs were incubated at 37°C ± 0.02°C and relative humidity of 50-60%
Parameters

No parameters are specified for this exposure.

Exposure 2

Main characteristics
Frequency
  • unspecified
Type
Exposure duration calling mode for 30, 48 or 72 hours (mobile phone was called every 30 minutes for 10 seconds)
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.77 W/kg - - - -

Exposure 3

Main characteristics
Frequency
  • unspecified
Type
Exposure duration talking mode for 30, 48 or 72 hours (mobile phone was kept in talking mode for 10 minutes every hour)
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.77 W/kg - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In group 3, closing of the neural tube was completed only after 72 hours, while in the other groups this developmental stage was already completed after 48 hours.
In tissue slices of the neural tube received from group 3 after 30- and 48-hours exposure, the TUNEL assay showed significantly increased apoptosis rates compared to not exposed tissue slices.
The immunoreactivity of caspase-3 and caspase-8 was highest in group 3 at all time points in comparison to the other groups, while the immunoreactivity of caspase-9 was highest in group 2 after 72-hours exposure.
The authors conclude that exposure to mobile phones could have a deleterious effect on the neural tube development of chick embryos.

Study character:

Study funded by

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