Study type: Medical/biological study (experimental study)

Study of low-intensity 2450-MHz microwave exposure enhancing the genotoxic effects of mitomycin C using micronucleus test and comet assay in vitro. med./bio.

Published in: Biomed Environ Sci 2002; 15 (4): 283-290

Aim of study (acc. to author)

In this study possible synergistic gentoxic interactions of 2450 MHz microwaves and mitomycin C on human lymphocytes were investigated.

Background/further details

The irradiation precedes mutagenic treatment with mitomycin C.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: 2 h

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration 2 h
Modulation
Modulation type CW
Exposure setup
Exposure source
  • Magnetron
Parameters
Measurand Value Type Method Mass Remarks
power density 50 W/m² unspecified measured - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results of this study showed that low-intesity microwave exposure alone could neither induce DNA single-strand break nor increase the number of micronucleated cells on human lymphocytes in vitro. Furthermore the experimental results indicated that exposure increases the DNA damage effect induced by mitomycin C, in comet assay in vitro, when exposure preceded mitomycin C exposure. These synergistic effects could only be observed in comet assay, not in micronucleus test.

Study character:

Study funded by

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