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To study whether whole of gestation exposure of fetal mouse brain to mobile phone radiofrequency fields produces a stress response detectable by induction of heat shock proteins.
Pregnant mice (n=10) were exposed and prior to parturition on day 19, fetal brains (n=10, one fetal brain of each litter) were collected.
Positive controls were performed (thermal stress).
Modulation type: pulsed
ばく露時間: 60 min/day from day 1 to day 19 of gestation
|ばく露時間||60 min/day from day 1 to day 19 of gestation|
|Pulse width||0.6 ms|
|Repetition frequency||217 Hz|
|ばく露装置の詳細||mice placed in perspex tubes radially around the dipole antenna|
|Sham exposure||A sham exposure was conducted.|
|SAR||4 W/kg||-||-||whole body||-|
There was no induction of HSP32 or HSP70 in any brains, while HSP25 expression was limited to two brainstem nuclei and occured consistenly in exposed and non-exposed brains.
In conclusion, using HSP as oxidative stress marker, the data showed that whole gestation exposure of fetal mouse brains to mobile phone radiofrequency fields did not produce any stress response.