研究のタイプ: 医学/生物学の研究 (experimental study)

[携帯電話はウサギ精液の果糖を減少させ、クエン酸塩を減少させない:縦断研究] retracted

The Mobile Phone Decreases Fructose But Not Citrate in Rabbit Semen: A Longitudinal Study (RETRACTED).

掲載誌: Syst Biol Reprod Med 2009; 55: 181-187

精子の運動能にとって重要な精液成分である果糖クエン酸濃度に対する携帯電話電磁界(900MHz)の影響を30匹の成獣雄ウサギで調べた。30匹はランダムにばく露群、拘束対照群、自由行動対照群に等分した。ばく露群は、待ち受けモード携帯電話をケージ床に設置し、ばく露時にケージ内のプラスティック製仕切り版を寄せてウサギを拘束し、外性器が携帯電話アンテナに向き合うようにして、1日8時間、12週間ばく露した。拘束対照群ばく露無しで拘束のみ行い、ケージストレスの影響を評価した。精液は週1回採取した。その結果、ばく露群では10週目に果糖濃度の運動性精子がベースラインレベルから有意に低下することが示されたが、一方、3群とも、クエン酸濃度あるいは他の研究パラメータに有意な変化は認められなかったと報告している。

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研究目的(著者による)

To study the effect of exposure to electromagnetic irradiation emitted from the mobile phone on fructose and citrate level in sperms of rabbits. (The study was retracted by publisher (Krawetz and Heinink 2012).)

詳細情報

Both fructose and citrate are important components in semen that facilitate sperm motility: Fructose serves as primary energy source for ejaculated sperms and citrate may inhibit seminal plasma DNAse to maintain sperm motility.
30 adult male rabbits were randomly divided into three groups: 1) mobile phone exposure (n=11), 2) sham exposure group (n=11), and 3) cage control group (n=8). Semen analysis and sperm function tests were conducted weekly.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
ばく露時間: continuous for 8 hr/day during 12 weeks
  • 電界強度: 2.92 V/m average over time (at 0.5 cm distance)
  • 電界強度: 0.487 V/m average over time (at the most distant region of the cage)
  • SAR: 0.43 W/kg average over mass (whole body) (as defined in the mobile phone's handbook)

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 8 hr/day during 12 weeks
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
  • in standby mode
ばく露装置の詳細 50 cm x 25 cm x 35 cm cages with plastic partitions to keep the animals in a specific position during exposure; mobile phone's antenna fixed to the cage bottom opposing the animal's genitalia
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
電界強度 2.92 V/m average over time 推定値 - at 0.5 cm distance
電界強度 0.487 V/m average over time 推定値 - at the most distant region of the cage
SAR 0.43 W/kg average over mass 備考を参照のこと。 whole body as defined in the mobile phone's handbook

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露前
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

A significant decrease in both fructose levels and in the number of motile sperms was observed in the mobile phone exposure group at the 10th week and thereafter. However, there was no significant correlation between the decline in the levels of fructose and the sperm motility. The sham exposed animals showed a similar but significantly less decline in sperm motility. No significant changes in citrate levels or any other study parameters were found in the three animal groups throughout the study.
The authors conclude, that the pulsed radiofrequency emitted by the mobile phone kept in the standby mode affected sperm motility and fructose but not citrate levels in rabbit semen.

研究の種別:

研究助成

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