Study type: Medical/biological study (experimental study)

Effect of power-frequency magnetic fields on genome-scale gene expression in Saccharomyces cerevisiae. med./bio.

Published in: Radiat Res 2003; 160 (1): 25-37

Aim of study (acc. to author)

To clarify the existence of an effect of high-intensity 50 Hz magnetic fields on genome-wide gene expression in yeast.

Background/further details

As positive controls, the cells were exposed to aerobic conditions, heat (40 °C) or minimal medium.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuously for 24 h

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuously for 24 h
Additional info vertical mf
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 10 mT effective value - - 150 mT, 300 mT

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The magnetic field exposure did not cause significant changes in expression for proteins or genes that were related to heat-shock response, DNA repair, respiration, protein synthesis and the cell cycle.
The data provide no evidence that the magnetic field exposure alters the fundamental mechanism of translation and transcription in eukaryotic cells.

Study character:

Study funded by

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