Study type: Medical/biological study (experimental study)

Effects of GSM-modulated radiofrequency electromagnetic fields on mouse bone marrow cells. med./bio.

Published in: Radiat Res 2008; 170 (6): 803-810

Aim of study (acc. to author)

To study the functional ability of bone marrow cells from mice exposed to GSM signals to colonize lymphatic organs generating mature T cells and B lymphocytes and rescue lethally X-irradiated mice from death.

Background/further details

Lethally X-irradiated (9 Gy) mice were injected with medium alone or containing bone marrow cells from either radiofrequency electromagnetic field exposed or sham-exposed or cage control donor mice. Each group of recipient mice consisted of 16 mice, eight of them were killed 3 and 6 weeks after transplantation.
In this study, hematopoietic precursor cells are challenged to differentiate and proliferate under the pressure of a lymphopenic environment.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: 2 h/day, 5 days/week for 4 weeks
  • SAR: 2 W/kg average over mass (whole body)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration 2 h/day, 5 days/week for 4 weeks
Exposure setup
Exposure source
Chamber 12 cm x 12 cm x 120 cm TEM cell
Setup during exposure mice housed in transparent cylindrical perspex jigs that did not allow them to move
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2 W/kg average over mass measured and calculated whole body -

Reference articles

  • Nasta F et al. (2006): Effects of GSM-modulated radiofrequency electromagnetic fields on B-cell peripheral differentiation and antibody production.
  • Ebert S et al. (2005): Response, thermal regulatory threshold and thermal breakdown threshold of restrained RF-exposed mice at 905 MHz.
  • Ardoino L et al. (2005): A radio-frequency system for in vivo pilot experiments aimed at the studies on biological effects of electromagnetic fields.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data showed no effect of in vivo exposure to GSM-modulated radiofrequency fields on the ability of bone marrow precursor cells to colonize lymphoid organs and to differentiate in phenotypically and functionally mature T cells and B lymphocytes.

Study character:

Study funded by

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