Exposure duration: continuous 4 h/day, 7 days/week for 2 months
|Exposure duration||continuous 4 h/day, 7 days/week for 2 months|
|Chamber||rats were placed in polycarbonate cages between the two coils|
|Setup||a pair of Helmholtz coils (diameter of 95 cm), each with 320 turns of 2.5 mm copper wire mounted on a wooden frame; distance between the coils was 33 cm|
|Sham exposure||A sham exposure was conducted.|
|magnetic flux density||3 mT||-||measured||-||-|
In the exposed group, levels of lipid peroxidation significantly increased and enzyme activities of superoxide dismutase and glutathione peroxidase decreased compared with the sham exposed group.
The number of TUNEL-positive cells and caspase-3 immunoreactivity increased in the exposed rats compared with the sham exposed animals.
Electron microscopy revealed mitochondrial degeneration, reduction in myofibrils, dilated sarcoplasmic reticulum and perinuclear vacuolization in the exposed rats.
In conclusion, the data showed that the magnetic field exposure caused oxidative stress, apoptosis and morphologic damage in the myocardium of adult rats. The magnetic field-related changes could be the result of increased oxidative stress.