2.45-Gz wireless devices induce oxidative stress and proliferation through cytosolic Ca(2+) influx in human leukemia cancer cells med./bio.

Aim of study (acc. to author)

Background/further details

Endpoint

• cell viability/cell division/proliferation: cell viability and cell number
• oxidative stress, cytosolic calcium concentration

Exposure

• • 2.45 GHz
  • 2.45 GHz
  • microwaves
• • PW pulsed wave
  • wireless transmitter
• • co-exposure

Extended view Compact view

Methods Endpoint/measurement parameters/methodology

• cell viability/cell division/proliferation: cell number (trypan blue staining, hemocytometer), cell viability (MTT assay, spectrophotometry)
• oxidative stress: lipid peroxidation (via thiobarbituric acid reactive substances), level of reduced glutathione, enzyme activity of glutathione peroxidase, level of vitamin C (spectrophotometry) cytosolic calcium concentration with and without 2-APB (2-Aminoethoxydiphenyl borate; a TRPM2 blocker (transmembrane protein TRP melastatin 2, a non-selective calcium-permeable cation channel)) (fluorophotometry)

Main outcome of study (acc. to author)

Study funded by

• not stated/no funding

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