Study type: Medical/biological study (experimental study)

Studying the protein expression in human B lymphoblastoid cells exposed to 1.8-GHz (GSM) radiofrequency radiation (RFR) with protein microarray. med./bio.

Published in: Biochem Biophys Res Commun 2013; 433 (1): 36-39

Aim of study (acc. to author)

To investigate the protein expression in human B-cell lymphoblastoid cells intermittently exposed to a 1,8 GHz GSM radiofrequency field.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 1.8 GHz
Modulation type: pulsed
Exposure duration: intermittent (5 min fields on/10 min fields off) for 24 hours

Exposure 1

Main characteristics
Frequency 1.8 GHz
Type
Waveform
Exposure duration intermittent (5 min fields on/10 min fields off) for 24 hours
Modulation
Modulation type pulsed
Additional info

GSM-like signal

Exposure setup
Setup no details in the article (exposure according to reference articles)
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2 W/kg - - - -

Reference articles

  • Zhijian C et al. (2010): Impact of 1.8-GHz radiofrequency radiation (RFR) on DNA damage and repair induced by doxorubicin in human B-cell lymphoblastoid cells.
  • Zeng Q et al. (2006): Effects of global system for mobile communications 1800 MHz radiofrequency electromagnetic fields on gene and protein expression in MCF-7 cells.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In the exposure group, a total of 20 proteins was significantly up-regulated and 7 were significantly down-regulated in comparison to the sham exposed group.Via Western blot, the results of two proteins, out of three that were examined, were validated.

Study character:

Study funded by

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