Study type: Medical/biological study (experimental study)

Increased protein synthesis by cells exposed to a 1,800-MHz radio-frequency mobile phone electromagnetic field, detected by proteome profiling. med./bio.

Published in: Int Arch Occup Environ Health 2010; 83 (6): 691-702

Aim of study (acc. to author)

To evaluate whether or not low intensity radiofrequency electromagnetic field exposure associated with mobile phone use can affect human cells, the authors used a sensitive proteome analysis method to study changes in protein synthesis in cultured human cells.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 1,800 MHz
Exposure duration: 5 min on - 10 min off for 8 hr

Exposure 1

Main characteristics
Frequency 1,800 MHz
Type
Exposure duration 5 min on - 10 min off for 8 hr
Additional info exposure with a signal mix of 66% GSM basic (talking mode) 34 % GSM-DTX (listening mode)
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2 W/kg - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

8 h exposure to the electromagnetic field caused a significant increase in protein expression in Jurkat cells and human fibroblasts, and to a lesser extent in activated primary human white blood cells. Quiescent (metabolically inactive) white blood cells did not detectably respond to the radiofrequency exposure. The increased protein expression was fully reversible within two hours. Since the radiofrequency exposure induced a temperature increase of less than 0.15°C, the authors suggest that the observed cellular response is a so called athermal effect. Possible mechanisms and explanations are discussed.

Study character:

Study funded by

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