Study type: Medical/biological study (experimental study)

Cell viability and growth in a battery of human breast cancer cell lines exposed to 60 Hz magnetic fields. med./bio.

Published in: Radiat Res 2000; 153 (5) Pt 2: 725-728

Aim of study (acc. to author)

The cell viability and cell growth of normal breast cells and breast cancer cells exposed to low frequency magnetic field in vitro should be investigated.

Background/further details

Four human breast cancer cell lines were selected differing in their hormone receptor status to clarify the hypothesis whether hormone-dependent cells react more sensitive to magnetic field.
In a further step the role of magnetic field exposure on artificial induced cytotoxicity was examined.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 60 Hz
Exposure duration: continuous for 72 h

Exposure 1

Main characteristics
Frequency 60 Hz
Type
Waveform
Polarization
Exposure duration continuous for 72 h
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 1 mT - - - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Magnetic field exposure had no effect on cell viability or cell growth in any cell line examined. Similarly, magnetic field exposure had no effect on artificial induced cytotoxicity.
The results show that magnetic field exposure does not exert influence on cell growth in breast cancer cells in vitro.

Study character:

Study funded by

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