Study type: Medical/biological study (experimental study)

No effect of extremely low-frequency magnetic field observed on cell growth or initial response of cell proliferation in human cancer cell lines. med./bio.

Published in: Bioelectromagnetics 2002; 23 (5): 355-368

Aim of study (acc. to author)

To investigate the cell proliferation response to residential or occupational magnetic field exposure in human cancer cell lines in vitro.

Background/further details

Experiments were performed up to three times.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 20–180 Hz
Exposure duration: 18 h, 24 h, 3 days
Exposure 2: 50–60 Hz
Exposure duration: 3 days

Exposure 1

Main characteristics
Frequency 20–180 Hz
Type
Waveform
Exposure duration 18 h, 24 h, 3 days
Additional info the experiments were done with i) a linearly polarized field i) a circularly polarized field ii) an elliptically polarized field
Exposure setup
Exposure source
Setup two pairs of Merritts three square coils with 40 inner turns and 78 outer turns; exposure space 30 cm x 30 cm x 30 cm
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2 µT effective value measured - vertical
magnetic flux density 20 µT effective value measured - vertical
magnetic flux density 100 µT effective value measured - vertical
magnetic flux density 500 µT effective value measured - vertical
magnetic flux density 500 µT effective value measured - rotating

Exposure 2

Main characteristics
Frequency 50–60 Hz
Type
Waveform
Exposure duration 3 days
Additional info these experiments were done with i) a circularly polarized field ii) an elliptically polarized field
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 485 µT - measured - Bv for the elliptical field
magnetic flux density 121 µT - measured - Bh for the elliptical field
magnetic flux density 500 µT effective value measured - for the circular field
magnetic flux density 354 µT - measured - Bv = Bh for the circular field

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No effect of magnetic field exposure of different field polarization and magnetic flux densities was observed on either cell growth or the initial response (G1 phase) of cell proliferation in five human cancer cell lines.

Study character:

Study funded by

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