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A novel experimental system was used to study the localized effects of microwave irradiation on eye lenses in culture for over 2 weeks. The purpose of the study was to focus on effects that are not caused by global temperature increase (temperature is maintained constant at 35°C).
|ばく露時間||intermittent, 50 min on/10 min off, for 8 days (192 cycles)|
|チャンバの詳細||The exposure system consisting of four transmission lines was placed in an incubator maintained at 35°C.|
|ばく露装置の詳細||Each lens was placed in a vessel and completely immersed in tissue culture medium. The vessel was inserted between the two metallic plates forming the transmission line that were of the same width as their separation. The medium filled the vessel up to the height of the plates. The configuration was designed to maximize both the uniformity and the intensity of the field in the lens region (11-12 mm height and 15-16 mm diameter).|
|Additional information||Four lenses were exposed simultaneously while four control lenses were kept in another incubator at the same temperature for the same period of time without any exposure to MW radiation.|
The authors found clear evidence that this irradiation has a significant impact on the eye lens. At the macroscopic level, it is revealed that exposure to a few mW at 1 GHz for over 36 h affects the optical function of the lens. Self-recovery occurs if the irradiation is interrupted.
At the microscopic level, close examination of the lens indicates that the interaction mechanism is completely different from the mechanism-causing cataract via temperature increase. Even if macroscopically the lens has recovered from the exposure, microscopically the indicators of irradiation impact remain.