研究のタイプ: 医学/生物学の研究 (observational study)

[勤務時間延長および無線周波電磁放射の状況下でのメラトニンおよびストレスホルモンの変動] med./bio.

Variations of melatonin and stress hormones under extended shifts and radiofrequency electromagnetic radiation.

掲載誌: Rev Environ Health 2005; 20 (2): 151-161

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研究目的(著者による)

To study the time-of-day variations in urinary levels of 6-sulphatoxy melatonin and three stress hormones in operators working fast-rotating extended shifts (16 to 18 h with a 24 h-stay in the station (9:00 to 9:00) followed by 3 days off) under radiofrequency electromagnetic radiation.

詳細情報

The excretion rate of the hormones was monitored at 4-hour intervals in a group of 36 male operators comprising 12 broadcasting station operators (high level of exposure), 12 TV station operators (low-level of exposure), and a control group of 12 satellite station operators (very low level of exposure).
This study is a part of complex investigation of the health risk assessment of occupational radiofrequency electromagnetic irradiation exposure (National Center of Hygiene, Medical Ecology and Nutrition, Report No 2.1/0.1: Assessment of the effect of low-level radiofrequency EMR on secretion of melatonin, the level of stress hormones and cardiovascular system. National Center of Hygiene, Medical Ecology and Nutrition, Sofia, Bulgaria, 2003; 1-128.).

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 6–25 MHz
ばく露時間: repeated exposure for 1 day on and 3 days off
ばく露2: 66.5–900 MHz
ばく露時間: repeated exposure for 1 day on and 3 days off
ばく露3: 5.85–6.245 GHz
ばく露時間: repeated exposure for 1 day on and 3 days off

ばく露1

主たる特性
周波数 6–25 MHz
タイプ
  • electromagnetic field
ばく露時間 repeated exposure for 1 day on and 3 days off
ばく露装置
ばく露の発生源/構造
  • broadcasting (BC) station
ばく露装置の詳細 Three groups of 12 operators each were investigated working fast-rotating extended shifts in three telecommunication stations, i.e., a broadcasting (BC) station, a TV station and a satellite (SAT) station, respectively. The operators from the three groups worked a 4-day cycle schedule: one extended shift (16 to 18 h) with a 24-h stay in the station, followed by 3 days off.
Additional information From the measurements and calculations, it was concluded that the level of exposure of BC station operators was high, whereas that of TV and SAT station operators was low, the lowest in SAT operators. The latter group was used as a control because no other suitable group could be found in terms of shift system and job characteristics.
パラメータ
測定量 種別 Method Mass 備考
電力密度 3.1 µW/cm² average over time 測定値および計算値 - TWAmean
電力密度 137 µW/cm² average over time 測定値および計算値 - TWAmax

ばく露2

主たる特性
周波数 66.5–900 MHz
タイプ
  • electromagnetic field
ばく露時間 repeated exposure for 1 day on and 3 days off
ばく露装置
ばく露の発生源/構造
  • TV station
パラメータ
測定量 種別 Method Mass 備考
電力密度 1.89 µW/cm² average over time 測定値 - TWAmean
電力密度 5.24 µW/cm² average over time 測定値 - TWAmax

ばく露3

主たる特性
周波数 5.85–6.245 GHz
タイプ
  • electromagnetic field
ばく露時間 repeated exposure for 1 day on and 3 days off
ばく露装置
ばく露の発生源/構造
  • satellite (SAT) station
パラメータ
測定量 種別 Method Mass 備考
電力密度 1.6 µW/cm² average over time 測定値 - TWAmean
電力密度 3.57 µW/cm² average over time 測定値 - TWAmax

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中

研究の主なアウトカム(著者による)

Radiofrequency electromagnetic irradiation had no effect on the typical diurnal pattern of 6-sulphatoxy melatonin. High-level radiofrequency electromagnetic irradiation exposure significantly increased the excretion rates of cortisol, adrenaline, and noradrenaline, whereas changes under low-level exposure did not reach significance.
In conclusion, the excretion of 6-sulphatoxy melatonin retained a typical diurnal pattern under extended shifts and radiofrequency electromagnetic irradiation, but showed an exposure-effect relation with stress hormones.

研究の種別:

研究助成

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