研究のタイプ: 医学/生物学の研究 (experimental study)

[神経内分泌系へのパルス高周波電磁界の影響] med./bio.

Effects of pulsed high-frequency electromagnetic fields on the neuroendocrine system.

掲載誌: Neuroendocrinology 1998; 67 (2): 139-144

この研究は、円偏波アンテナから放射されたパルス高周波電磁界(217 Hzパルス変調900 MHz電磁界平均電力密度 0.02 mW / cm2)が健康なヒトの神経内分泌系に及ぼす影響を調べた。睡眠ポリグラフによる監視下で、成長ホルモン(GH)、コルチゾール黄体形成ホルモンLH)およびメラトニンの夜間ホルモンプロファイルを測定した。その結果、電磁界ばく露(1時間継続)の開始直後に、コルチゾール血清レベルにおける視床下部 - 下垂体 - 副腎軸活動が僅かに一過性で上昇した; GH、LHおよびメラトニンについては、夜間の全ホルモン産生および分泌パターンの動的特性の両方に関して、擬似ばく露条件と比較して、ばく露条件下で有意な影響は見られなかった;また、睡眠脳電図データの評価結果も、ばく露条件下で有意な変化を示さなかったが、REM抑制効果の傾向が見られた、と報告している。

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研究目的(著者による)

To investigate the influence of pulsed high-frequency electromagnetic fields in the lower microwave frequency range generated by a digital mobile telephone on the neuroendocrine system (hormone secretion) in healthy humans.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for 8 h

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
偏波
  • circular
ばく露時間 continuous for 8 h
Modulation
Modulation type pulsed
Pulse width 577 µs
Repetition frequency 217 Hz
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
  • GSM system, amplifier
Distance between exposed object and exposure source 40 cm
チャンバの詳細 The subjects slept in a specially constructed metal-free bed that was enclosed in a metal-free chamber lined with RF-absorbing material.
ばく露装置の詳細 The antenna was positioned beneath the head of the bed at a distance of 40 cm to the vertex of the subject and was operated from the neighbouring room via an extension lead.
Sham exposure A sham exposure was conducted.
Additional information After an adaptation night, polysomnographies were performed during two successive nights. The subjects were exposed in one night and sham-exposed in the other night (randomized and blinded).
パラメータ
測定量 種別 Method Mass 備考
電力密度 0.02 mW/cm² mean - - at 40 cm

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中

研究の主なアウトカム(著者による)

The only significant effect found was an interaction between field exposure and time for cortisol concentration. This indicates an alterated temporal secretion pattern of cortisol under exposure. A transient elevation in the cortisol serum level immediately after onset of field exposure was found which persisted for 1h. For growth hormone, luteinizing hormone, and melatonin, no significant effects were found under radiation compared to the placebo condition, regarding both total hormone production during the night and dynamic characteristics of the secretion pattern. The evaluation of the sleep EEG data revealed no significant effects under radiation compared to the placebo condition. However, an indication of an REM sleep suppressive effect could be found. The data indicate that weak high-frequency electromagnetic fields have no effects on nocturnal hormone secretion except for a slight elevation in cortisol production which is transient (pointing to an adaption of the organism to the stimulus).

研究の種別:

研究助成

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