この研究は、円偏波アンテナから放射されたパルス化高周波電磁界（217 Hzパルス変調900 MHz電磁界、平均電力密度 0.02 mW / cm2）が健康なヒトの神経内分泌系に及ぼす影響を調べた。睡眠ポリグラフによる監視下で、成長ホルモン（GH）、コルチゾール、黄体形成ホルモン（LH）およびメラトニンの夜間ホルモンプロファイルを測定した。その結果、電磁界ばく露（1時間継続）の開始直後に、コルチゾール血清レベルにおける視床下部 - 下垂体 - 副腎軸活動が僅かに一過性で上昇した； GH、LHおよびメラトニンについては、夜間の全ホルモン産生および分泌パターンの動的特性の両方に関して、擬似ばく露条件と比較して、ばく露条件下で有意な影響は見られなかった；また、睡眠脳電図データの評価結果も、ばく露条件下で有意な変化を示さなかったが、REM抑制効果の傾向が見られた、と報告している。
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To investigate the influence of pulsed high-frequency electromagnetic fields in the lower microwave frequency range generated by a digital mobile telephone on the neuroendocrine system (hormone secretion) in healthy humans.
Modulation type: pulsed
ばく露時間: continuous for 8 h
|ばく露時間||continuous for 8 h|
|Pulse width||577 µs|
|Repetition frequency||217 Hz|
|Distance between exposed object and exposure source||40 cm|
|チャンバの詳細||The subjects slept in a specially constructed metal-free bed that was enclosed in a metal-free chamber lined with RF-absorbing material.|
|ばく露装置の詳細||The antenna was positioned beneath the head of the bed at a distance of 40 cm to the vertex of the subject and was operated from the neighbouring room via an extension lead.|
|Sham exposure||A sham exposure was conducted.|
|Additional information||After an adaptation night, polysomnographies were performed during two successive nights. The subjects were exposed in one night and sham-exposed in the other night (randomized and blinded).|
|電力密度||0.02 mW/cm²||mean||-||-||at 40 cm|
The only significant effect found was an interaction between field exposure and time for cortisol concentration. This indicates an alterated temporal secretion pattern of cortisol under exposure. A transient elevation in the cortisol serum level immediately after onset of field exposure was found which persisted for 1h. For growth hormone, luteinizing hormone, and melatonin, no significant effects were found under radiation compared to the placebo condition, regarding both total hormone production during the night and dynamic characteristics of the secretion pattern. The evaluation of the sleep EEG data revealed no significant effects under radiation compared to the placebo condition. However, an indication of an REM sleep suppressive effect could be found. The data indicate that weak high-frequency electromagnetic fields have no effects on nocturnal hormone secretion except for a slight elevation in cortisol production which is transient (pointing to an adaption of the organism to the stimulus).