研究のタイプ: 医学/生物学の研究 (experimental study)

[ヒト正中神経に対する50 Hz、1 mTの磁界の影響] med./bio.

Influence of 50 Hz-1 mT magnetic field on human median nerve.

掲載誌: Electromagn Biol Med 2012; 31 (4): 285-292

この研究は、健常なボランティア6人(28-52歳;平均35歳)の前腕部正中神経電力周波磁界ばく露を行い、神経伝導機構の変化の可能性を調べた。磁界ばく露は、50Hzヘルムホルツコイルに前腕を通して行われ、磁界強度は約1mTとした。磁界ばく露前、磁界ばく露実験中、ばく露終了後の3回、正中神経の遠位部または近位部にそれぞれ刺激頻度2Hz、パルス幅0.2msの最大上刺激を与え、そのときの短母指外転筋(APB)の応答(活動電位振幅)を記録した。その結果、(遠位刺激時の振幅)/(近位刺激時の振幅)の比は、ばく露後に比べばく露前では有意に低かったことを報告している。

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研究目的(著者による)

To examine whether exposure of humans to 50 Hz-magnetic fields influences the nerve conduction mechanism in the arm.

詳細情報

6 healthy volunteers were examined. Measurements were performed three times for every proband: 1.) before exposure, 2.) during exposure and 3.) after exposure. The median nerve from the right arm was stimulated on the elbow and on the wrist with pulses (0.2 ms, 2 Hz). The motor responses were recorded from the Abductor pollicis brevis muscle (abductor of the thumb), using surface electrodes.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 50 Hz
ばく露時間: continuous for 5 min

ばく露1

主たる特性
周波数 50 Hz
タイプ
  • magnetic field
波形
  • sinusoidal
ばく露時間 continuous for 5 min
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 pair of Helmholtz coils with a diameter of 10 cm and 220 turns of 0.8 mm gauge copper wire placed parallel to the table, mounted on a plastic frame, 15 cm apart, connected in series; arm of the test person placed in the axial position in the coils
パラメータ
測定量 種別 Method Mass 備考
磁束密度 1 mT - 測定値および計算値 - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
  • peripheral nervous system
調査の時期:
  • ばく露前
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

No significant differences were seen between the measurements during the exposure and the measurements before and after the exposure. However, a significant decrease in the stimulus conduction was observed in the measurements after the exposure when compared to the measurements before the exposure.
The authors conclude that these results could indicate a potential deleterious effect of 50 Hz-magnetic field exposure on human nerves.

研究の種別:

研究助成

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