研究のタイプ: 医学/生物学の研究 (experimental study)

Effects of the magnetic field constituted by the incubators on the behavior models of newborn rats. med./bio.

掲載誌: Ponte 2016; 72 (4) Pt 1: 17-27

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研究目的(著者による)

To examine the potential adverse effects of extremely low frequency magnetic fields of incubators for newborns on the behavior of young rats.

詳細情報

Fourty-eight newborn rats of five dams were randomly divided into three groups (n=16 per group): 1) control group, 2) sham exposure (kept in the incubator, but switched off) and 3) exposure group (kept in the incubator). Rat pups were kept together with their mothers. They were exposed for 15 days and examined when they were 1-month old.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 50–60 Hz
ばく露時間: continuously for 15 days

ばく露1

主たる特性
周波数 50–60 Hz
タイプ
  • magnetic field
ばく露時間 continuously for 15 days
ばく露装置
ばく露の発生源/構造
  • incubator
ばく露装置の詳細 rats were exposed in a standard Plexiglas cage put inside the incubator with a mattress; cage was located at 36.8 cm from the left edge of the mattress where the magnetic flux density was highest
Sham exposure A sham exposure was conducted.
Additional information sham exposed rats were handled like the exposed ones, however, the incubator was switched off and noise was created by a air fan placed at a distance of 10 m
パラメータ
測定量 種別 Method Mass 備考
磁束密度 2.7 µT - 測定値 - heater on
磁束密度 0.21 µT - 測定値 - heater off

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

Remark EMF-Portal: All statistical calculations in this article are based on the median.
In the Morris water maze, the amount of time for finding the platform was significantly increased in exposed rats (group 3) compared to sham exposed rats (group 2) and those from the control group (group 1). In the open field test, the duration at the central zone was significantly shorter in the exposed animals compared to groups 1 and 2. Furthermore, significantly less vertical movements, higher number of groomings (only significant compared to group 2), and a higher number of micturitions were observed in the exposed animals compared to groups 1 and 2 (if not stated otherwise). In the elevated plus maze, no significant differences in the staying duration in the open and closed arms was found between the groups. However, the number of groomings, defecations and micturitions was significantly higher in the exposed animals compared to groups 1 and 2.
The authors conclude that extremely low frequency magnetic fields of an incubator for newborns could have an adverse effect on anxiety and spatial learning in young rats.

研究の種別:

研究助成

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