Study type: Medical/biological study (experimental study)

Combined exposure to extremely low frequency (ELF) magnetic fields and chemical mutagens: Lack of genotoxic effects in human lymphocytes med./bio.

Published in: Electro Magnetobiol 2001; 20 (3): 331-341

Aim of study (acc. to author)

This study was conducted to investigate the induction of genotoxic and cytotoxic effects in human lymphocytes in vitro following co-exposure to 50 Hz sinusoidal magnetic field and chemical mutagen.

Background/further details

Blood samples were taken from 10 healthy, non-smoking volunteers, aged between 27 to 58 years. Applied chemical mutagens were mitomycin C (25 and 50 ng/ml) and hydroquinone (60 µM).



Exposure Parameters
Exposure 1: 50 Hz

Exposure 1

Main characteristics
Frequency 50 Hz
Exposure setup
Exposure source
Chamber Incubator
Setup Plexiglas layer in middle of coil structure hosted the samples in cylindrical culture flasks (10 cm diameter, 4 cm high).
Measurand Value Type Method Mass Remarks
magnetic flux density 1 mT effective value measured - -

Reference articles

  • Scarfi MR et al. (1999): Micronucleus frequency and cell proliferation in human lymphocytes exposed to 50 Hz sinusoidal magnetic fields

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The exposure to magnetic field alone did not affect the micronucleus incidence, but a slight increase in cell proliferation could be observed.
Co-exposure did not increase the damage due to the chemical treatments alone, both in the terms of genotoxicity (micronuclei formation) and cell proliferation.

Study character:

Study funded by

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