Study type: Medical/biological study (experimental study)

50-Hz, 1-mT sinusoidal magnetic fields do not affect micronucleus frequency and cell proliferation in human lymphocytes from normal and Turner's syndrome subjects. med./bio.

Published in: Electro Magnetobiol 1997; 16 (3): 301-307

Aim of study (acc. to author)

To investigate the effect of a sinusoidal magnetic field (50 Hz, 1 mT) on cell proliferation and micronucleus frequency in human lymphocytes in vitro.

Background/further details

A previous study to pulsed magnetic field exposure (publication 2071) was performed,- here a sinusoidal magnetic field exposure was applied.
Lymphocyte cultures from five subjects affected by Turner's syndrome (mean age 14 years) and from five healthy donors (mean age 28 years) were examined. From each sample a electromagnetic field exposed and sham exposed culture was set up.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: 72 h

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration 72 h
Exposure setup
Exposure source
Chamber incubator
Additional info cells occupied a volume where the MF uniformity was about +/- 2%.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 1 mT effective value measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No statistically significant differences in micronucleus frequency and cell proliferation were observed between control group and exposed group from healthy and Turner`s syndrome subjects.
These data indicate that the electromagnetic field investigated does not exert any genotoxic effect nor interfere with cell cycle.

Study character:

Study funded by

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