To study whether extremely low frequency magnetic fields may contribute to mutagenesis or carcinogenesis.
In a previous study (publication 10460) the authors have found that exposure of unstimulated human blood cells to 50 Hz, 1 mT for 2 h did not induce any DNA damage. The aim of this investigation is to study the potential genotoxic effect of a longer exposure time on PHA-stimulated human blood cells.
In order to evaluate the possible genotoxic effects of extremely low frequency magnetic fields, human blood cells were exposed in vitro. Extremely low frequency pretreated cells were also irradiated with 1 Gy of X-ray to study the possible combined effect of extremely low frequency magnetic fields and ionizing radiation.
|Exposure duration||continuous for 48 h|
Data do not evidence any DNA damage induced by extremely low frequency magnetic fields exposure or any effect on cell proliferation. Results obtained from the combined exposure (extremely low frequency magnetic fields and ionizing radiation) do not suggest any synergistic or antagonistic effect.