Study type: Medical/biological study (experimental study)

No apoptosis is induced in rat cortical neurons exposed to GSM phone fields med./bio.

Published in: Bioelectromagnetics 2007; 28 (2): 115-121

Aim of study (acc. to author)

To investigate whether the exposure to radiofrequency electromagnetic fields causes effects on neuronal apoptosis in vitro.

Background/further details

The positive controls were with the protein kinase inhibitor staurosporine treated cells. The apoptosis rate was measured 0 hours and 24 hours after exposure.



Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 24 h

Exposure 1

Main characteristics
Frequency 900 MHz
Exposure duration continuous for 24 h
Modulation type pulsed
Pulse width 0.577 ms
Repetition frequency 217 Hz
Additional info

GSM signal

Exposure setup
Exposure source
  • wire-patch cell (WPC)
Chamber The WPC was placed in a "box" with RF absorbing ferrite walls [Laval et al., 2000; Joubert et al., 2006]. An identical sham "box" was placed in the same incubator at 37 °C, 5% CO2.
Setup The WPC allowed simultaneous and equal exposure of eight 35-mm Petri dishes.
Sham exposure A sham exposure was conducted.
Additional info Control cells were placed in another identical incubator at the same time.
Measurand Value Type Method Mass Remarks
SAR 0.25 W/kg mean measured and calculated - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In this study no statistically significant difference in the apoptosis rate was observed between controls and 24 hours GSM-exposed rat cortical neurons, either 0 hours or 24 hours post-exposure.
All three methods used to assess apoptosis were concordant.

Study character:

Study funded by

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