Study type: Medical/biological study (experimental study)

Effect of GSM-900 and -1800 signals on the skin of hairless rats. II: 12-week chronic exposures. med./bio.

Published in: Int J Radiat Biol 2006; 82 (9): 675-680

Aim of study (acc. to author)

To study whether the cells of hairless rat skin are affected by chronic local exposure (12 weeks) to GSM-900 or -1800 radiofrequency irradiation.

Background/further details

To perform positive controls rats were exposed to UV-B radiation.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 2 h/day, 5 days/week, for 12 weeks
Exposure 2: 1,800 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 2 h/day, 5 days/week, for 12 weeks

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration repeated daily exposure, 2 h/day, 5 days/week, for 12 weeks
Modulation
Modulation type pulsed
Exposure setup
Exposure source
Setup Animals were restrained in rocket type plastic tubes and exposed using a loop antenna located on the right side of the back that could be moved as the animal was growing.
Sham exposure A sham exposure was conducted.
Additional info For positive control, two rats were exposed to UVB irradiation (400 mJ/cm²).
Parameters
Measurand Value Type Method Mass Remarks
SAR 2.5 W/kg - - - -
SAR 5 W/kg - - - -

Exposure 2

Main characteristics
Frequency 1,800 MHz
Type
Exposure duration repeated daily exposure, 2 h/day, 5 days/week, for 12 weeks
Modulation
Modulation type pulsed
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2.5 W/kg - - - -
SAR 5 W/kg - - - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No major histological alterations were found in the studied cellular parameters after the 12 week local exposure to GSM-900- or -1800 (2.5 or 5 W/kg). No difference in epidermis thickness was detected among the animal groups. Radiofrequency exposure did not affect cell proliferation. Filaggrin, collagen, and elastin were not modified by exposure to GSM signals.

Study character:

Study funded by

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