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To study the effect of microwave exposure on lipid peroxidation status in rats.
The effect of administration of the antioxidants ascorbic acid and alpha-tocopherol was also studied.
120 rats were divided into the following groups (each group = 5 rats): Six groups served as control group, six groups were microwave exposed, six groups were treated with ascorbic acid, and six groups were treated with alpha-tocopherol (both four days before exposure). The lipid peroxidation was monitored for a period of 8 weeks post irradiation.
ばく露時間: not given in the article
For further information on the setup see also: Guy A. W, Dosimetry of Exposure to VLF to Microwaves, Health Physics. 1987; 56: 1 - 6.
Animals were divided into the following groups: i) microwave exposure ii) microwave exposure + 1 mg/kg ascorbic acid - 4 days before exposure iii) microwave exposure + 1 mg/kg alpha-tocopherol - 4 days before exposure iv) control
|ばく露時間||not given in the article|
|Distance between exposed object and exposure source||12 cm|
|チャンバの詳細||irradiation chamber surfaces lined with water|
The microwave exposure caused an increase in the lipid peroxidation within the first 24 hours after exposure, and then gradually reduced to the value of the control group after about one week. Ascorbic acid and alpha-tocopherol administration caused a decrease of the control value of the lipid peroxidation within the first week after irradiation.
The data demonstrated that microwave exposure caused significant increase in the lipid peroxidation status and there were protective effects of the antioxidants ascorbic acid and alpha-tocopherol.