研究のタイプ: 医学/生物学の研究 (experimental study)

[Wistarラットの過酸化状態に対する2.45 GHzマイクロ波ばく露の影響] med./bio.

Effects of 2.45 GHz microwave exposures on the peroxidation status in Wistar rats.

掲載誌: Niger Postgrad Med J 2003; 10 (4): 243-246

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研究目的(著者による)

To study the effect of microwave exposure on lipid peroxidation status in rats.

詳細情報

The effect of administration of the antioxidants ascorbic acid and alpha-tocopherol was also studied.
120 rats were divided into the following groups (each group = 5 rats): Six groups served as control group, six groups were microwave exposed, six groups were treated with ascorbic acid, and six groups were treated with alpha-tocopherol (both four days before exposure). The lipid peroxidation was monitored for a period of 8 weeks post irradiation.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 2.45 GHz
ばく露時間: not given in the article

General information

For further information on the setup see also: Guy A. W, Dosimetry of Exposure to VLF to Microwaves, Health Physics. 1987; 56: 1 - 6.
Animals were divided into the following groups: i) microwave exposure ii) microwave exposure + 1 mg/kg ascorbic acid - 4 days before exposure iii) microwave exposure + 1 mg/kg alpha-tocopherol - 4 days before exposure iv) control

ばく露1

主たる特性
周波数 2.45 GHz
タイプ
  • electromagnetic field
ばく露時間 not given in the article
ばく露装置
ばく露の発生源/構造
  • microwave generator Toshiba ER6660E + antenna
Distance between exposed object and exposure source 12 cm
チャンバの詳細 irradiation chamber surfaces lined with water
パラメータ
測定量 種別 Method Mass 備考
電力密度 6 mW/cm² maximum 測定値 - -

Reference articles

  • Lai H et al. (1995): [急性で低強度のマイクロ波ばく露はラット脳細胞でのDNA一本鎖切断を増加させる]
  • McRee DI et al. (1984): [2.45 GHzマイクロ波放射にばく露したラットの全身および局所のドシメトリ]

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

The microwave exposure caused an increase in the lipid peroxidation within the first 24 hours after exposure, and then gradually reduced to the value of the control group after about one week. Ascorbic acid and alpha-tocopherol administration caused a decrease of the control value of the lipid peroxidation within the first week after irradiation.
The data demonstrated that microwave exposure caused significant increase in the lipid peroxidation status and there were protective effects of the antioxidants ascorbic acid and alpha-tocopherol.

研究の種別:

研究助成

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