Study type: Medical/biological study (experimental study)

Chromosome damage and micronucleus formation in human blood lymphocytes exposed in vitro to radiofrequency radiation at a cellular telephone frequency (847.74 MHz, CDMA). med./bio.

Published in: Radiat Res 2001; 156 (4): 430-433

Aim of study (acc. to editor)

The aim of the study was to investigate the extent of possible genetic damage caused by radiofrequency irradiation (847.74 MHz CDMA) on human blood lymphocytes in vitro.



Exposure Parameters
Exposure 1: 847.74 MHz
Modulation type: CW
Exposure duration: continuous for 24 h

Exposure 1

Main characteristics
Frequency 847.74 MHz
  • guided field
Exposure duration continuous for 24 h
Modulation type CW
Additional info


Exposure setup
Exposure source
Setup The experimental setup using a radial transmission line facility and the method used for SAR determination have been described in the reference article.
Additional info For each blood sample three sterile T-75 culture flasks were used, each containing 4 ml of blood diluted with 36 ml of culture medium. Two flasks were used for RF and sham exposures, and a third flask was exposed to 1.5 Gy γ radiation as positive control.
Measurand Value Type Method Mass Remarks
power 75 W - - - net forward power
power density 950 W/m² - - - -
SAR 4.9 W/kg mean - - -
SAR 5.5 W/kg mean - - -

Reference articles

  • Vijayalaxmi et al. (2001): Cytogenetic studies in human blood lymphocytes exposed in vitro to radiofrequency radiation at a cellular telephone frequency (835.62 MHz, FDMA).

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The overall cytogenetic responses of the lymphocytes were similar although the absolute values were slightly different. The mitotic indices, the indices of abnormal cells showing chromosomal damage, and the numbers of exchange aberrations were not significantly different between radiofrequency irradiation and sham-exposed cells. Similarly, the percentages of binucleated cells, the incidence of binucleated cells with one, two or three micronuclei, and the total numbers of micronuclei were not significantly different.

Study character:

Study funded by

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